Preface to BIT 53:3

PREFACE

Preface

PREFACE

Dev118745 533..543

The primary glial cells in the retina, the Müller glia, differentiate from retinal progenitors in the first postnatal week. CNTF/LIF/STAT3 signaling has been shown to promote their differentiation; however, another key glial differentiation signal, BMP, has not been examined during this period of Müller glial differentiation. In the course of our analysis of the BMP signaling pathway, we observ...

Jgp_201711759 533..546

533 Introduction The dual premise that inherited monogenic errors in membrane ion currents cause disease, and that drugs designed to restore the biophysics of defective voltage-gated channels hold the key to correcting them is over 50 years old and remains unshaken. Breakthroughs in visualizing, modeling, and optically controlling pore regions of voltage gated-channels, including alternative vo...